Amantadine administration is associated with impulse control disorders in PD

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Amantadine and cognitive flexibility: decision making in Parkinson’s patients with severe pathological gambling and other impulse control disorders

INTRODUCTION Dopamine replacement therapy for Parkinson's disease (PD) was recently linked to the development of impulse control disorders such as pathological gambling (PG), hypersexuality, compulsive shopping, and binge or compulsive eating. Antiglutamatergic agents including amantadine (Ama) reduce these behaviors in PD and non-PD patients. The aim of our study is to evaluate the changes in ...

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ژورنال

عنوان ژورنال: Nature Reviews Neurology

سال: 2011

ISSN: 1759-4758,1759-4766

DOI: 10.1038/nrneurol.2010.206